To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most genetic medicine uses viruses or double-stranded DNA to deliver genetic ...

Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

A new family of enzymes enables precise cuts in single-stranded DNA, offering powerful new tools for genetic engineering and expanding possibilities in biotechnology. (Nanowerk News) A few years ago, ...

Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...

A new long-read sequencing technique has helped researchers investigate how DNA mutations arise in a variety of contexts. A collaboration of researchers led by NYU Langone Health and NYU Grossman ...

Mutations are changes in the molecular 'letters' that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including ...

An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...