San Francisco 49ers vs Carolina Panthers picks, predictions, odds, win probabilities for NFL Week 12 Monday Night Football game Nov. 24. Who will win?

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 on a 53-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Monday Night Football in Week 17 is a huge game for the Los Angeles Rams, as they’re looking to bounce back from a tough loss to the Seattle Seahawks in Week 16

Complete team stats and game leaders for the Philadelphia Eagles vs. Buffalo Bills NFL game from December 28, 2025 on ESPN.

The Bills are facing the Eagles for the first time since 2023 and only the fifth time since 2011. In the most recent 2023 matchup, Buffalo lost a close game to Philadelphia in overtime. Eagles kicker Jake Elliott sent it into OT with a 59-yard field goal with just 20 seconds left in the game.